Bayesian identification of bacterial strains from sequencing data
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چکیده
منابع مشابه
Bayesian identification of bacterial strains from sequencing data
Rapidly assaying the diversity of a bacterial species present in a sample obtained from a hospital patient or an environmental source has become possible after recent technological advances in DNA sequencing. For several applications it is important to accurately identify the presence and estimate relative abundances of the target organisms from short sequence reads obtained from a sample. This...
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Background Fast, accurate and high-throughput detection of bacteria is in great demand. The present work was conducted to investigate the possibility of identifying both known and unknown bacterial strains from unassembled next-generation sequencing reads using custom-made guide trees. Results A program named StrainSeeker was developed that constructs a list of specific k-mers for each node of ...
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BACKGROUND Fast, accurate and high-throughput identification of bacterial isolates is in great demand. The present work was conducted to investigate the possibility of identifying isolates from unassembled next-generation sequencing reads using custom-made guide trees. RESULTS A tool named StrainSeeker was developed that constructs a list of specific k-mers for each node of any given Newick-f...
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ژورنال
عنوان ژورنال: Microbial Genomics
سال: 2016
ISSN: 2057-5858
DOI: 10.1099/mgen.0.000075